Evidence library

Peptides.

Peptides are a drug class, not a single longevity strategy. Evidence ranges from an approved medicine for a narrow condition to compounds promoted online without controlled human efficacy or adequate product characterization.

6 evidence-ranked entries
Important limitations

What the evidence cannot settle yet

A hormone change, animal healing result, or benefit in a specific disease does not establish anti-aging, physique, or recovery benefits in healthy people. Combination products are especially difficult to assess when the mixture itself has never been tested.

Safety themes

Risks depend on the intervention

Endocrine effects, glucose changes, fluid retention, injection reactions, and unknown long-term risks require attention. Unapproved or compounded injections add sterility, identity, potency, impurity, and immunogenicity uncertainty.

Strongest current evidence

Strong evidence leads this category

Ratings compare confidence in each entry's stated benefit—not whether every intervention is appropriate or recommended.

How ratings work
Browse the evidence

Every peptides entry

Sorted from stronger to weaker evidence.

Open Tesamorelin
Strong
Peptides

Tesamorelin

An approved growth-hormone-releasing peptide that reduces visceral fat in HIV-associated lipodystrophy but is not a general weight-loss or anti-aging treatment.

Open Collagen Peptides
Emerging
Peptides

Collagen Peptides

Oral hydrolyzed collagen may modestly improve skin hydration or elasticity, but study quality and industry funding temper confidence.

Open GHK-Cu
Emerging
Peptides

GHK-Cu

A copper-binding peptide with plausible skin and wound biology but sparse controlled human evidence and no established role for injectable anti-aging use.

Open BPC-157
Insufficient
Peptides

BPC-157

An unapproved research peptide promoted for healing despite an evidence base dominated by animal studies and unresolved safety questions.

Open CJC-1295 + Ipamorelin
Insufficient
Peptides

CJC-1295 + Ipamorelin

A marketed growth-hormone peptide stack with no controlled combination trial, ambiguous product identity, and major compounded-injection evidence gaps.

Open Human Growth Hormone
Insufficient
Peptides

Human Growth Hormone

A prescription hormone with established replacement indications but an unfavorable benefit-risk profile for healthy-aging or physique use.